C4 Therapeutics, Inc.
C4 Therapeutics, Inc. (CCCC) is listed on NASDAQ and classified in Biotechnology, part of the Healthcare sector. It is headquartered in Watertown, United States and has 104 employees. The company is worth $391.22M. Revenue was $35.95M in fiscal 2025, up 1.0% from the year before. It reported a net loss of $104.99M. The share price is 38.5% below its 52-week high of $5.17. 5 of the 38 superinvestors we track held it at the end of Q2 2026. The largest position belongs to Ken Griffin (Citadel Advisors), at $19.56M. In that quarter, 2 of them opened or added to the position and 2 reduced it. No open-market insider trades in it were filed over the last 30 days.
Written from the data on this page: SEC filings (13F, Form 4, annual reports) and market prices.
Year by year, from the annual reports; dividends from the payments themselves.
Bars are year-end balances; lines are what happened during the year.
Major managers that reported this stock in their latest 13F.
▼ -92.6% over 5Y.
today you would have $62.25▼ -93.8%
Dividends reinvested, splits accounted for. Past prices say what happened, not what will.
The last 6 closed years, each at that year’s closing price and reported numbers.
| Indicator | Median | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Year-end price | $1.91 | $3.60 | $5.65 | $5.90 | $32.20 | $33.13 | |
| P/S | 9.3x | 5.2x | 7.2x | 18.7x | 9.3x | 34.3x | — |
| P/B | 1.4x | 0.7x | 1.2x | 1.6x | 1.0x | 4.0x | 5.1x |
| EPS | -$1.27 | -$1.52 | -$2.67 | -$2.62 | -$1.82 | -$5.83 | |
| Profit margin | -295.96% | -292.08% | -295.96% | -638.34% | -412.19% | -183.23% | — |
| ROE | -42.62% | -40.92% | -48.76% | -53.83% | -44.32% | -21.53% | -23.62% |
Median of the years shown; P/E years above 200x are left out.
Companies of similar size in Healthcare, for comparison. The columns are the same ones above, in the same order.
| Stock | Price | P/E | P/B | Dividend yield | ROE | Market cap |
|---|---|---|---|---|---|---|
| CAPRCapricor Therapeutics Inc | $6.71 | — | 1.6x | 0.00% | -73.70% | $390.11M |
| EMBCEmbecta Corp. | $6.86 | 4.5x | — | 4.66% | — | $388.68M |
| AUNAAUNA S.a | $5.32 | 88.7x | 0.8x | 0.00% | 1.62% | $393.98M |
| TRXBTRex Bio, Inc. | $14.01 | — | — | 0.00% | — | $384.51M |
| EDITEditas Medicine, Inc. | $2.49 | — | 3.6x | 0.00% | -118.82% | $382.41M |
| SRTAStrata Critical Medical, Inc. | $4.54 | — | 1.4x | 0.00% | -9.22% | $401.64M |